Cognitive impairment can happen to anyone. From a head injury to the early signs of Alzheimer’s disease, cognitive impairment can have a significant and lasting impact. Early detection can improve quality of life. Until now, traditional cognitive assessments like MMSE or MiniCog have been challenging to administer and often slow to report results.

  • Head injury/Concussion
  • Alzheimer’s disease
  • Other dementia disorder
  • Substance misuse
  • Prescription drug misuse or adverse effects
  • Type 2 Diabetes
  • Stroke/cerebrovascular disease
  • Depression
  • Sleep issues
  • Vitamin B12 deficiency
  • Cancer and metastases

Cognitive impairment can impact anyone

  • Early signs of dementia or Alzheimer’s disease
  • Traumatic brain injury
  • Concussion and other indications

Early and accurate detection is important

  • Early detection leads to finding the root cause
  • Improves quality of life
  • Faster and more objective than MMSE and MiniCog

New cognitive technology from Quest Diagnostics

  • iPad-based app easily administered in around 10 minutes
  • Immediate results with cognitive score
  • Integration with most EMRs

Rethinking the cost and quality of healthcare

We know that the pace and cost of practicing healthcare can be demanding, and efficiency is everything. CogniSense™ was designed to help optimize healthcare delivery and reduce cost.

  • CogniSense™ is affordable and easy-to-administer
  • An objective understanding of the extent of cognitive impairment can improve patient compliance, which can reduce costly hospital readmissions
  • App administration and results interpretation are easy to learn and understand
  • An accurate diagnosis can help avoid unnecessary admission to skilled nursing or assisted living facilities.

“I’ve had patients who are PhDs who’ve scored 30/30 on MMSE, even though we knew they were demented.”


Dr. William M. Duke, Internist and Geriatrician

Rethinking patient care

CogniSense™ gives you access to a new vital statistic…your patients’ cognitive score. Now, you can objectively identify, measure, and track their cognitive status. And the more you know, the more you can do.

  • Testing can accurately categorize patients as normal, having MCI, 
and dementia
  • Patients appreciate the convenience and simplicity of the test
  • CogniSense™ generates an objective score on the patient’s cognition that can be tracked and monitored over time, informing treatment and long-term care decisions*
  • With a patient’s cognitive score, you may have a clearer picture of the potential impact of surgical procedures or major operations
  • An accurate diagnosis can improve a patient’s medication and treatment compliance, which can help reduce hospital readmissions

“Having a tool like CogniSense™ elevates the service level my practice provides.”


Harry Jacob, MD, Chief Medical Officer, Primary PartnerCare ACO

Rethinking cognitive technology

CogniSense™ is the first all-digital tool of its kind offered by Quest Diagnostics. After just minutes with a qualified healthcare professional, you and your patient get a reliable cognitive score for memory, orientation, and executive organization that can inform your healthcare decisions.

  • CogniSense’s unique delivery system assesses memory, orientation, and executive organization in as little as ten minutes
  • The app makes administration and scoring easy and reliable CogniSense™ performed favorably compared to paper-based gold standard MMSE and Mini-Cog tests2,4
  • Results are delivered in a detailed PDF report that captures the physician’s interpretation stored digitally in the Quest Care360® online portal, and can be pushed to other compatible EMRs
  • Deploying the assessment requires minimal training and has a short learning curve

CogniSense™ is the first all-digital tool of its kind, performing favorably when compared to paper-based gold standard MMSE and Mini-Cog tests.2,3 After just minutes with a qualified healthcare professional, you get a reliable cognitive score for memory, orientation, and executive organization that can be tracked over time to measure patient patterns to inform healthcare decisions.


How CogniSense Works

icon-1 Sign Up

Download the free CogniSense™ app from the Apple App Store and connect it with your Care360 account. If you don’t already have a Care360 account, you can register here.

icon-2 Perform Assessment

Your patient data is pulled over from Care360. Find the patient and begin the assessment. 

icon-3 Track Results

Results are sent to Care360, where you can track progress over time. Or, send the results to other healthcare providers as needed.

Case Examples

Alcohol-Induced Cognitive Impairment

A married couple over age 70 was known to their physician to have problems with alcoholism. During their annual wellness visit, the husband explained that his wife was having some memory problems. The physician administered CogniSense™ for both the husband and wife.

The husband’s score indicated normal cognition. The wife’s score indicated severe cognitive impairment.

The physician engaged in a dialogue about the impact alcohol can have on cognition and memory and advised a change in lifestyle. The CogniSense™ results led to more targeted patient management, addressing alcohol intake and cognition at every visit.

80-Year-Old Female with Suspected Cognitive Dysfunction

An 80-year-old female presented with mild forgetfulness. Her daughter expressed concern despite high functionality and no detectable impairment in physician’s office.

The physician didn’t think there was a cognitive problem and administered CogniSense™ based on the daughter’s concern. The physician was surprised that the patient scored extremely low.

Based on the results of the CogniSense™ assessment, the physician ordered a full neurological workup, which included advanced testing, and the physician will now routinely monitor her cognition.


50-Year-Old Bank Manager with Concussion

A 50-year-old bank manager suffered a concussion. After receiving emergency treatment at a hospital, including imaging that came back negative, the patient was released with a concussion diagnosis. After one week, the patient still didn’t feel right and a friend reported her as being “fuzzy”.

Her primary care physician conducted a neurological exam, which was normal. He then conducted the CogniSense™ assessment. She scored below normal for a woman of her age and education level.

The physician recommended keeping her out of work for an extended period of time due to the mental and physical risks associated with her cognitive state. When she returned for a follow-up exam, she was reassessed and scored normal and was able to return to work.


Confirmed dementia

A physician was treating an 80-year-old patient with a history of mild to moderate dementia as well as stage 4 lung cancer. The patient was struggling, and it was necessary for the physician to discuss with the family the patient’s ability to make healthcare decisions or to transition to palliative care.

The patient’s family was reluctant to admit that the patient was struggling to make informed decisions. The physician used CogniSense™ to provide an objective measure of the patient’s cognitive ability. The patient scored low, in the single digits.

Marijuana impacts cognitive ability

A 66-year-old male was visiting his doctor after his wife complained of his memory issues. The patient passed a simple three-word memory exam. The physician administered CogniSense™ and the patient received an abnormal score.

After seeing the score, the patient’s wife insisted that her husband tell his physician of his “bad habit. He told his physician ” that he had been smoking six to eight marijuana cigarettes per day. The physician explained the potential cognitive impact and insisted that the patient stop using marijuana.

Microvascular infarct

A 75-year-old male has hypertension and hyperlipidemia. He was visiting his physician for a follow-up for these conditions. The physician noticed a slight decrease in cognitive function and administered CogniSense™.

The patient scored very low. The physician ordered lab tests and an MRI of the brain revealing microinfarct disease.

Intraventricular bleed

A 72-year-old female came to her physician with her son for a hypertension follow-up. Her son expressed some concerns about changes in his mother’s memory and behavior. A neurological exam performed by her primary care physician was normal and CogniSense™ was administered.

The patient scored extremely low. Because of the rapid onset, the physician made a same-day appointment with neurology.

Lack of sleep and stress-induced cognitive impairment

A 68-year-old working executive with an advanced graduate degree was seen by his physician for his annual wellness visit. His wife expressed that she was concerned about her husband’s memory.

The physician conducted the CogniSense™ assessment and was shocked when the patient received a low score.

CogniSenseTM helps patients and caregivers

It’s never easy when you or a loved one begins to show signs of memory loss or cognitive decline. The first thing we think of is “Alzheimer’s”. That’s not always the cause of cognitive impairment. There are many causes of cognitive decline, and many of them are treatable. No matter what the cause, it’s important to find out early how an individual’s cognitive function is affected.

CogniSenseTM provides a cognitive “score” which can be tracked over time. This helps provide a diagnosis and gauge the appropriate follow up and treatment.

Here's What to Expect

Doctor Visit

Your doctor’s office can perform this evaluation in as little as ten minutes. It’s a simple interactive tool which assesses language, speech, memory, and motor function.

Review Results

Results are available as soon as the evaluation is complete. The result is a cognitive “score” which is stored in your patient record.


Based on the score and other clinical factors, your physician will make a recommendation for follow-up, and if needed, a treatment and management plan should be established. After a period of time, you should be reassessed to identify any cognitive change since the last visit.





1. Clionsky M, Clionsky E. Identifying cognitive impairment during the Annual Wellness Visit: who can you trust? J Fam Pract. 2011 Nov;60(11):653-9. 2. Clionsky M, Clionsky E. Development and Validation of the Memory Orientation Screening Test (MOST™): A Better Screening Test for Dementia. Am J Alzheimers Dis Other Demen. 2010 Dec;25(8);650-6. doi: 10.1177/1533317510386216. 3. Clionsky M, Clionsky E. The Memory Orientation Screening Test (MOST™) accurately separates normal from MCI and Demented Elders in a prevalence stratified sample. J Alzheimers Dis Parkinsonism 2013, 3:109: doi: 10.4172/2161-0460.1000109. 4. Clionsky M, Clionsky E. Psychometric equivalence of a paper-based and computerized (iPad) version of the Memory Orientation Screening Test (MOST), The Clinical Neuropsychologist, in press.